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Dr. Keith Easterling,
NBB, Emory worked on a new course NBB470H - Neuropathology. Keith
basically began the development of a multimedia hypertextbook for
this course. We are hoping to make the materials available after
this summer on ScienceNET. As Keith states, "The course was designed
to provide information about fundamental neuroanatomy and then,
as a second focus, to bring clincians and students together for
a discussion of specific neurological diseases that have relatively
clearcut relationships to abnormalities in the function of specific
brain regions. However, a one-semester undergraduate course couldn't
possibly provide a comprehensive coverage. Ideally, a text would
have been assigned, but the various specific topics were much more
in-depth than a "general" text would allow for, while the general
overview was still needed. Additionally, guests and students were
at different physical locations, and the materials and lectures
were in custom-written (multimedia) formats -- word, powerpoint,
hybrids, etc. For instance, most digital formats were instructor-written,
but incorporated links to web-based pictures that were available
at other sites. Overall, it was a big improvment over the old black-and-white
handout method that I might have resorted to. These materials really
needed to be portable, changeable, and easy to integrate into a
more general "background" overview. Both Learnlink and Blackboard
were "piloted" during the course of the semester because they each
have their strengths. Blackboard was a much better venue for providing
rigidly structured information to the students. I set up a series
of lectures, weblinks and readings on it. On Learnlink, I gave assignments,
moderated discussions, and facilitated contact between the faculty
and students involved in the course."
Below is a sample page from KeithÕs multimedia outlines
with links to more detailed websites.
Pathology of Prurulent Types
- Hyperemia of meningeal vessels and outpouring of polymorphonuclear
(PMN) leukocytes
- Location of the subarachnoid exudate- pus
tends to accumulate along the course of cortical veins
- Cerebral
edema- slight to moderate
- Nerve cells appear normal at this stage, though function
may be deranged
- CSF - mostly PMN, high protein, low sugar, high pressure,
and positive
cultures
- May heal with complete resolution but can heal with fibrosis
and hydrocephalus.
- Meningococcal
meningitis frequently accompanied by meningococcemia, myocarditis,
petechial adrenal hemorrhage, and sudden death.
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