Trion Dubose-Arnold, chemistry teacher at Southside High School in Atlanta Public Schools, created two complete investigative cases for her chemistry classes. Girls Gone Wild involves a group of cheerleaders who are disqualified from a competition because an unknown white powder is discovered in their hotel room. Students must help investigators to discover the composition of the unknown white powder through a laboratory activity and deductive reasoning. Two different options for assessment, a technical report from the laboratory to the police or a comic strip depicting the story's events and laboratory procedures, allow students to choose their own assignment.

For another case, Ms. Dubose-Arnold created a mock newspaper article describing a diving accident in which a young diver ascended too quickly and suffered from decompression syndrome or "the bends". Students are compelled to create a diving safety brochure outlining the signs, symptoms, etiology, and physiologic basis for decompression syndrome. The brochure must also include discussion of how the gas laws apply to scuba diving.