SURE: Articles from Past SURE Programs

Research Indicates New Theory of Microbial Biodiversity
Joshua Wilcox

Evolutionary science has long taken it for granted that plant and animal species are genetically related to each other the closer they are geographically. For example, two individuals of a species of pine tree in New Jersey would be more genetically similar when compared to each other than one of these individuals and a pine tree in Georgia of the same species. Looking at the genetic differences in microbes is a different story. It has been a long-standing theory that microbes of the same species have little to no genetic variation throughout the world and any geographic variation would be related to climate, not genetic variation. "The motto for microbes has been, 'Everything is everywhere, but the environment selects,' " explains John Taylor, professor of plant and microbial biology at UC Berkeley's College of Natural Resources.


Looking at this "motto," Rachel Whitaker, a graduate student in Taylor's lab traveled to hot springs around the world, taking samples of a specific species of a microbe, Sulfolobus islandicus, as well as looking at existing samples taken from similar sites. The research indicated that the separate cultures had very small, but significant genetic differences between populations living in different geographic regions. "If this type of geographic pattern occurs in other microbes, it means the microbial world is even more diverse than we had previously predicted, which is astounding," expounded Whitaker.


The implications this study might have on how scientists examine pathogens could be significant. A slight genetic variation could mean the difference between a workable cure and a complete dud. Species of the same pathogen often emerge in different parts of the world and the knowledge that these microbes could vary genetically inside of the same species could be invaluable as researchers develop more specific treatments.