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Cells regulate the expression of their genes in response
to changes in their environment. Comparison of expression arrays
from different cell samples is proving to be useful in providing
insight into and information about important genes and their functions.
Through the use of DNA Microarray we examined the gene expression
two different mice and two different monkeys infected with WNV and
SIV respectively. Select genes from the following biological pathways
were expressed (and thus potentially critical) in the resistant
organisms: (1) Response to biotic stimulus (2) Intracellular protein
transport (3) Cell organization and biogenesis (4) Cell proliferation.
Additional significant similarities and differences will be reported
as an initial survey of viral resistance.
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